Last edited by Dulabar
Monday, July 20, 2020 | History

5 edition of High Density Lipoproteins and Atherosclerosis III found in the catalog.

High Density Lipoproteins and Atherosclerosis III

Proceedings (International Congress Series)

by N. E. Miller

  • 21 Want to read
  • 20 Currently reading

Published by Excerpta Medica .
Written in English


The Physical Object
Number of Pages280
ID Numbers
Open LibraryOL7532129M
ISBN 100444814426
ISBN 109780444814425

High-Density Lipoproteins—Atherosclerosis. Nikkila, Kaste, Ehnhold and Viikari, Acta Medica Scandinavica (), measured serum high-density lipoprotein-cholesterol (HDL-C) levels in twenty-eight epileptic patients who received PHT. These were compared with ninety healthy controls, forty-four men and forty-nine women. The fatty acid portion of VLDL is released to adipose tissue and muscle in the same way as for chylomicrons, through the action of lipoprotein lipase. The action of lipoprotein lipase coupled to a loss of certain apoproteins (e.g. apoC-II) converts VLDL to intermediate density .

Lipoprotein disorders. The major classes of lipoproteins are chylomicrons, very-low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). Disorders that affect lipid metabolism may be caused by defects in the structural proteins of lipoprotein particles, in the cell receptors that recognize the various types. Koeller J and Talbert R L, "Modification of high-density lipoprotein cholesterol in the management of cardiovascular risk", Pharmacotherapy (), Oct; 22 (10): pp. 1,,, Meyers C D and Kashyap M L,"Pharmacologic elevation of highdensity lipoproteins: recent insights on mechanism of action and atherosclerosis protection", Curr. Opin Author: Raif Tawakol.

Intermediate-density lipoproteins and progression of coronary artery disease in hypercholesterolemic men. Lancet. ; Google Scholar; 6 NIH Consensus Development Panel on Triglyceride, High-Density Lipoprotein, and Coronary Heart Disease. NIH Consensus Conference: Triglyceride, High-Density Lipoprotein, and Coronary Heart by:   Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J ; Zilversmit DB. Atherogenesis: a postprandial phenomenon. Circulation ; McNamara JR, Shah PK, Nakajima K, Cupples LA, Wilson PW, Ordovas JM.


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High Density Lipoproteins and Atherosclerosis III by N. E. Miller Download PDF EPUB FB2

High levels of low-density lipoprotein (LDL) can eventually build up within the walls of your blood vessels and narrow the passageways. Sometimes a clot can form and get stuck in the narrowed space, causing a heart attack or stroke.

This is why LDL cholesterol is often referred to as "bad" cholesterol. High-density lipoprotein cholesterol. High-density lipoprotein (HDL) is one of the five major groups of lipoproteins.

Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules around the body within the water outside are typically composed of 80– proteins per particle (organized by one, two or three ApoA; more as the particles enlarge picking up and carrying more fat.

A complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies. With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical by: Cholesterol, triglycerides, and high-density lipoproteins are important constituents of the lipid fraction of the human body.

Cholesterol is an unsaturated alcohol of the steroid family of compounds; it is essential for the normal function of all animal cells High Density Lipoproteins and Atherosclerosis III book is a fundamental element of their cell membranes.

It is also a precursor of various critical substances such as adrenal and gonadal Cited by: Get this from a library. High density lipoproteins and atherosclerosis III: proceedings of the 3rd International Symposium on Plasma High Density Lipoproteins and Atherosclerosis, San Antonio, March [N E Miller; Alan R Tall;].

INTRODUCTION. A large number of studies has clearly shown the existence of a strong inverse correlation between plasma high-density lipoprotein cholesterol (HDL-C) concentrations and the incidence of coronary heart disease (CHD) [1,2], but the significance of such association has been recently ention clinical trials carried out with agents efficient in raising HDL-C levels Cited by: low high-density lipoprotein Low serum concentrations of HDL cholesterol have consistently emerged as an independent risk factor for CHD.

In the Framingham Study 63 and the Quebec Cardiovascular Study, 64 there was a well-defined escalation in risk as HDL cholesterol levels decreased. High-density Lipoproteins. HDL consist of a series of lipoprotein particles of relatively high density, all of which contain apo A-I.

A proportion of HDL particles also contain apo A-II. Some HDL species (HDL 3) are more dense than others (HDL 2). HDL particles are composed largely of byproducts of catabolism of TAG-rich lipoproteins.

(A) Increased plasma low-density lipoproteins and decreased high-density lipoproteins levels, (B) hyperglycaemia, and (C) obesity are major cardiovascular risk factors. Through various mechanisms, these risk factors directly or indirectly stimulate the production of myeloid cells (monocytes, neutrophils, and reticulated platelets) increasing.

In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing.

Density increases from chylomicrons (CM, of lowest density) through lipoproteins of very low density, intermediate density and low density (LDL), to high density lipoproteins.

HDL can be separated, on the basis of density, into two metabolically distinct subtypes: HDL2 (density –) and. Role of High Density Lipoproteins in Atherosclerosis. Written By: Claudia Guy, ND. The topic of cholesterol is still a hot topic in medicine since it is generally considered the leading cause of atherosclerosis, a type of cardiovascular disease.

But cholesterol goes far beyond heart disease. This book is an excellent resource for educating physicians and scientists about dyslipidemia and HDL metabolism, including many exogenous substances which interact with and influence HDL. Readers will benefit from the unique visual exposition and the insights of international experts.

Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein which transport all fat molecules around the body in the extracellular water. These groups, from least dense to most dense, are chylomicrons (aka ULDL by the overall density naming convention), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein and high-density.

Tall AR. Plasma high density lipoproteins. Metabolism and relationship to atherogenesis. J Clin Invest ; Mendivil CO, Rimm EB, Furtado J, et al. Low-density lipoproteins containing apolipoprotein C-III and the risk of coronary heart disease.

Circulation ; Davignon J, Gregg RE, Sing CF. Their role is to transport water-insoluble lipids in the blood. On the basis of their buoyant density lipoproteins are divided into 5 major classes: chylomicrons, very low density lipoproteins (VLDL), intermediate density lipoproteins (IDL), low density lipoproteins (LDL) and high density lipoproteins (HDL).

Part III is devoted to atherosclerosis and lipoproteins. Part IV takes up the clinical aspects of hyperlipoproteinemias.

Part V on methods contains two studies—the first on the isolation of human plasma high density lipoproteins; the second on the separation. 48% of apo-b molecule, structural protein of chylomicrons, produced by same gene that produces apo-b, but post-transcriptional editing of the RNA involves a deamination and this occurs only in the intestine (CAA to UAA - stop codon), lacks LDL receptor binding site.

Heterogeneity in the Conformation of Apo A-I on the Surface of HDL Particles.- Structural Properties of the Heparin-Binding Domains of Human Apolipoprotein E.- Characterization and Metabolism of Glycated High Density Lipoproteins in Diabetic Patients.- Pages: a combination of high.

ow, and very low density lipoproteins in the blood that is commonly used to assess heart disease risk - L:6, p. Triglycerides three fatty acids joined to a glycerol molecule; the most common configuration of lipid in the body - L:6, p.

LDL indicates low-density lipoprotein; HDL, high-density lipoprotein. Acceptable, borderline high, and high categories for total and LDL cholesterol and acceptable, borderline low, and low for HDL cholesterol are based on guidelines from the National Cholesterol Education Program Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents.

16 To convert total, LDL, Cited by:   Kannel WB, High-density lipoproteins: epidemiologic profile and risks of coronary artery disease, Am J Cardiol, ;52(4):9B–12B. Crossref | PubMed; DeGoma EM, Leeper NJ, Heidenreich PA, Clinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterol, J Am Coll Cardiol, ;51(1)–Author: Esther Godfrey, Julian Pj Halcox.One: Lipoprotein Deficiency and Atherosclerosis.- Genetic High Density Lipoprotein Deficiency States and Atherosclerosis.- Metabolic Interrelationships of HDL Subclasses.- Speciation of HDL.- Modifications and Degradation of High Density Lipoproteins.- Effect of Diabetes Mellitus and End-Stage Renal Disease on HDL Metabolism